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Book Review: The Fast 800 Diet by Michael Mosley – Learn How the Fast 800 Can Work With GLP-1 Medication

The pursuit of health and wellness has led to the creation of various diet plans, each promising unique benefits. Among these, The Fast 800 Diet by Dr. Michael Mosley stands out, combining the principles of intermittent fasting, a low-carb Mediterranean diet, and time-restricted eating. Dr. Mosley, a well-known advocate of science-backed diets, brings his expertise to the forefront in this book, providing readers with a comprehensive guide to achieving weight loss and improving overall health.

After spotting this book at a thrift store, I picked it up a few years ago. I had thumbed through it, interested in the Mediterranean aspect and the recipe section. I was doing Weight Watchers then, and I always keep my eyes open for higher lean protein recipes so that this one would be worth the cost and the read. For me, fasting means stopping to snack at night and only eating in the morning once you are hungry. But really, putting forth that practice daily doesn’t work for me. So, I left that part of the book behind and kept the rest. I did try a few of the recipes, all yummy. And then, I put the book aside. 


When I started on my GLP-1 journey a few months ago, I started looking through all of my “diet” books for information that would correlate with the new information I had learned while taking the GLP-1 injectables. As I reread this one, I realized so much made sense. While I do not recommend anyone do 800 calories long term, it can be a way to jumpstart your new lifestyle and clean up your diet to get you on the Mediterranean path.  It is important to remember that GLP-1 medications are not a diet. They are complete lifestyle overhaul.

In this review, I will explore the key aspects of The Fast 800 Diet, its foundational principles, potential benefits, and drawbacks. We’ll also consider how it compares to other diets in the wellness landscape.

Understanding the Basics of The Fast 800 Diet

Dr. Michael Mosley introduces The Fast 800 Diet as a hybrid approach, combining rapid weight loss with sustainable, long-term health benefits. The diet is built on three pillars:

#1. Intermittent Fasting: Central to The Fast 800 Diet is intermittent fasting, a practice that involves cycling between periods of eating and fasting. Dr. Mosley advocates for the 16:8 method, where you fast for 16 hours and eat within an 8-hour window. This approach is designed to help the body switch to fat-burning mode, promoting weight loss and improving metabolic health.

#2. 800-Calorie Days: Another critical element is the low-calorie intake during the initial phase of the diet. Participants are encouraged to consume just 800 calories per day for the first two weeks. This calorie restriction is meant to kickstart rapid weight loss and set the stage for sustainable eating habits in the long run.

#3. Low-Carb Mediterranean Diet: After the initial 800-calorie phase, the diet transitions to a low-carb Mediterranean approach. This means embracing healthy fats, lean proteins, and plenty of vegetables while minimizing sugar and refined carbohydrates. Dr. Mosley emphasizes the benefits of the Mediterranean diet, which is known for its heart-healthy properties and its ability to maintain weight loss.

The Science Behind The Fast 800 Diet

Dr. Mosley’s The Fast 800 Diet is not just a diet plan; it’s grounded in scientific research. The book offers a deep dive into the science of metabolism, explaining how intermittent fasting and calorie restriction can lead to significant health improvements.

Intermittent Fasting and Metabolic Health

Intermittent fasting has gained popularity in recent years, and Dr. Mosley thoroughly explains why it works. Limiting the eating window encourages the body to use its stored fat for energy, leading to weight loss. Additionally, fasting helps to regulate insulin levels, reduce inflammation, and improve overall metabolic health. Dr. Mosley also discusses how intermittent fasting can lower the risk of chronic diseases such as type 2 diabetes and cardiovascular disease.

The Role of Calorie Restriction

The 800-calorie phase is arguably the most challenging aspect of the diet, but it is also the most crucial for rapid weight loss. Dr. Mosley draws on studies that show how short-term calorie restriction can lead to significant fat loss, particularly in the abdominal area. This phase is designed to be temporary, to reset eating habits and encourage long-term adherence to a healthier lifestyle.

The Mediterranean Diet Advantage

The final phase of The Fast 800 Diet incorporates the principles of the Mediterranean diet, which is well-regarded in the nutrition community for its health benefits. Dr. Mosley explains how this diet is rich in monounsaturated fats, omega-3 fatty acids, and antioxidants, all contributing to cardiovascular health. He also highlights the role of whole foods, such as olive oil, nuts, fish, and vegetables, in sustaining weight loss and promoting overall well-being.

Potential Benefits and Drawbacks

Like any diet plan, The Fast 800 Diet has pros and cons. While it offers a well-rounded approach to weight loss and health, it may not suit everyone.

Benefits of The Fast 800 Diet

Rapid Weight Loss: One of the primary benefits of The Fast 800 Diet is its potential for rapid weight loss. Many participants experience noticeable results within the first few weeks by significantly reducing calorie intake and incorporating intermittent fasting. This quick success can be a powerful motivator, encouraging individuals to stick with the plan and continue making healthier choices.

Improved Metabolic Health: The diet’s emphasis on intermittent fasting and Mediterranean approaches contributes to better metabolic health. Participants often see improved insulin sensitivity, reduced inflammation, and lower cholesterol levels. These changes aid in weight loss and reduce the risk of developing chronic diseases like type 2 diabetes and heart disease.

Sustainable Long-Term Habits: While the initial 800-calorie phase is designed for rapid weight loss, The Fast 800 Diet transitions into a more sustainable way of eating. Focusing on a low-carb Mediterranean diet helps participants develop healthier, long-term habits that are easier to maintain than more restrictive diets. This gradual shift supports weight maintenance and overall well-being.

Drawbacks of The Fast 800 

Diet Strict Initial Phase: The most challenging aspect of The Fast 800 Diet is the strict calorie restriction during the first phase. Consuming just 800 calories daily can be difficult, especially for those not accustomed to such a low intake. This phase requires careful meal planning and a strong commitment to meet nutritional needs, which might be overwhelming for some.

Not Suitable for Everyone: The diet’s low-calorie and intermittent fasting components may not be appropriate. Individuals with certain medical conditions, such as diabetes or eating disorders, should consult a healthcare professional before starting this diet. Additionally, pregnant or breastfeeding women should avoid the strict calorie restriction phase.

Potential for Weight Regain: As with any diet, there is a risk of regaining lost weight once the initial phase is over. Participants must carefully transition to the maintenance phase, following Dr. Mosley’s guidelines to prevent the common issue of yo-yo dieting. Ensuring a gradual increase in calorie intake and maintaining the Mediterranean diet principles are key to sustaining weight loss.

The Fast 800 Diet by Dr. Michael Mosley

Comparing The Fast 800 Diet to Other Diets

The Fast 800 Diet stands out in the crowded field of weight loss plans due to its combination of science-backed principles and flexibility. Unlike many fad diets that focus on extreme restriction or elimination of food groups, The Fast 800 Diet emphasizes a balanced approach, blending intermittent fasting, calorie control, and the Mediterranean diet.

Unlike ketogenic diets, which eliminate most carbohydrates, the Fast 800 Diet allows for a more balanced intake of nutrients while still encouraging fat burning through ketosis during fasting periods. Unlike purely low-calorie diets, which can lead to muscle loss and metabolic slowdown, the Fast 800 Diet incorporates nutrient-dense foods that help preserve muscle mass and support overall health.

How The Fast 800 Diet Can Work in Conjunction with GLP-1 Medications

The Fast 800 Diet and GLP-1 medications, such as semaglutide and tirzepatide, can be powerful allies in the quest for weight loss and improved metabolic health. GLP-1 (Glucagon-Like Peptide-1) medications work by mimicking a hormone that regulates appetite and insulin levels, leading to reduced hunger and better blood sugar control. When combined with the principles of The Fast 800 Diet, the effects of these medications can be amplified, creating a synergistic approach to weight management.

Enhanced Weight Loss: GLP-1 medications help reduce appetite and slow gastric emptying, making adhering to the low-calorie phases of The Fast 800 Diet easier. This can lead to more significant and sustained weight loss, as the medications support the diet’s goals of reducing calorie intake and promoting fat burning.

Improved Blood Sugar Control: GLP-1 medications and The Fast 800 Diet are known for their positive effects on blood sugar regulation. The diet’s focus on intermittent fasting and low-carb, nutrient-rich foods aligns well with the blood sugar-stabilizing effects of GLP-1 medications. This combination can be particularly beneficial for individuals with type 2 diabetes or insulin resistance.

Long-Term Sustainability: The transition from the 800-calorie phase to the Mediterranean diet in The Fast 800 Diet encourages the development of healthy, long-term eating habits. When paired with GLP-1 medications, which are often prescribed for long-term use, this approach can help individuals maintain their weight loss and metabolic health over time. The medications can assist in curbing cravings and preventing overeating, making it easier to stick with the diet’s principles in the long run.

Customized Approach: Working with a healthcare professional, individuals can tailor the combination of The Fast 800 Diet and GLP-1 medications to suit their specific needs. For instance, the timing of medication doses can be adjusted to align with fasting periods, maximizing the benefits of both strategies. This personalized approach ensures that the diet and medication work together effectively to achieve optimal results.

By integrating The Fast 800 Diet with GLP-1 medications, individuals can create a comprehensive and effective plan for weight loss and improved health. This combination leverages the strengths of both strategies, offering a powerful tool for those seeking to transform their health and well-being.

Final Thoughts on The Fast 800 Diet

The Fast 800 Diet by Dr. Michael Mosley offers a compelling approach to weight loss and health improvement. Combining the proven benefits of intermittent fasting, calorie restriction, and the Mediterranean diet provides a balanced and sustainable pathway to achieving health goals.

However, like any diet, it’s essential to consider personal health needs and consult with your healthcare professional before embarking on the journey. The strict nature of the initial phase might not be for everyone, but for those who can commit, the rewards can be significant. If you’re seeking a diet rooted in science and offering both short-term and long-term benefits, The Fast 800 Diet might be the key to unlocking your health and wellness potential.

If you’re ready to take control of your health and want to follow my journey, join me on Nevermore Lane as I share my experiences and tips on making the most of this transformative journey. Let’s embark on this path to better health together!

Check out some of my recent weight loss & Zepbound-related posts:

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